Top OTC Dandruff Shampoos for a Healthy Scalp

Effective OTC Dandruff Shampoos for All Hair Types

Do you know what type of shampoo is best for treating dandruff or you need a clinically proven dandruff shampoo? If you have an extremely itchy scalp and uncontrollable dandruff, you might have severe dandruff and therefore you might need a prescription strength shampoo for dandruff. A fungus called Malassezia naturally lives on most people's scalps and drugstore dandruff shampoo can help treat the condition and fortunately, there are anti-dandruff shampoos that can help control this problem.

They work by killing the fungus, reducing inflammation, and preventing it from growing back. As a dry shampoo lover who also has dandruff, the right shampoo matters. If you are looking for the best over-the-counter dandruff shampoo, we hope you find our recommendations and this Best OTC Dandruff Shampoo post helpful. 

There are two main types of shampoos for uncontrollable dandruff: medicated and non-medicated. Medicated shampoos contain substances like selenium sulfide, ketoconazole, or zinc pyrithione, which get rid of the fungus that causes dandruff. Non-medicated shampoos, on the other hand, use ingredients such as tea tree oil, salicylic acid, or coal tar to help exfoliate flakes and soothe the scalp.

If you're dealing with dandruff, especially uncontrollable dandruff, it's best to seek the advice of a medical expert to explore any possible underlying health concerns plus you could need prescription strength shampoo for dandruff. Dandruff could be a sign of a more serious condition like seborrheic dermatitis or psoriasis.

Gentle Yet Effective shampoos to get rid of dandruff

We have used all of the shampoos below over the past couple of years. At any time in our home, there 2-3 dandruff shampoos in our shower because of severe dandruff and itchy scalp plus a few people seem to suffer from uncontrollable dandruff a few times per year.

L'Oreal Paris EverPure Sulfate Free Scalp Care Detox Shampoo and Scalp Treatment

L'Oreal Paris EverPure Sulfate Free Scalp Care Detox Shampoo and Scalp Treatment: L'Oreal Paris EverPure Sulfate Free Scalp Care Detox is best paraben and sulphate free anti dandruff shampoo.This product is perfect for those with color-treated hair and dry scalp. It is free from sulfates, parabens, dyes, and gluten, making it 100% vegan. Hair colorists have validated this premium formula for its gentleness on hair color. Anti-fade and UV filter. Refreshing fragrance of mint and eucalyptus, combined with the benefits of menthol and neem leaf. This is also our top pick for dandruff shampoo for bleached hair. 

Head & Shoulders Clinical Strength Dandruff Shampoo

Head & Shoulders Clinical Strength Dandruff Shampoo: This Medicated Head and Shoulder ​is an absolute family favorite​ with manuka honey for scalp relief, menthol for a cooling, refreshing feeling and citrus for advanced oil control.​ ​Does head and shoulders get rid of dandruff​?​ ​This clinically proven dandruff shampoo most definitely does. ​Head and Shoulders Volumizing Shampoo works so well for my hair and gives me great volume. How does head and shoulders get rid of dandruff​?​ ​ Protect against uncontrollable dandruff and excess oil with Head and ​Shoulders dandruff antifungal shampoo. The v formula matches prescription dandruff shampoo with 2% ketoconazole, recommended by dermatologists. Infused with a refreshing citrus scent, it leaves you with healthy, vibrant hair.​

Artnaturals Tea Tree Shampoo and Conditioner

Artnaturals Tea Tree Shampoo and Conditioner: ArtNaturals tea tree shampoo and conditioner set contains 100% pure tea tree essential oil. This natural shampoo is paraben and sulfate free plus helps with uncontrollable dandruff. The anti itching, anti dandruff benefits of borage oil join forces with watercress extract, which keeps scalp moisturized, preventing dry:scalp triggered dandruff and flakiness. This set stimulates new hair growth by clearing out dead skin cells from hair follicles.  ArtNaturals offers a 100% satisfaction guaranteed or your money back.

JASON Dandruff Relief Treatment Shampoo

JASON Dandruff Relief Treatment Shampoo: JASON Dandruff Relief Treatment Shampoo gently cleanses and nourishes hair while controlling scalp dermatitis and mild psoriasis. A combination of sulfur and salicylic acid treats mild psoriasis and dermatitis to help eliminate flakes and itchiness. This medicated cleanser also contains rosemary, olive and jojoba oils, which unite to soothe, heal and moisturize the scalp. They make their Dandruff Relief products with safe, gentler and effective ingredients.

Nizoral A-D Anti-Dandruff Shampoo

Nizoral A-D Anti-Dandruff Shampoo: This Nizoral itchy scalp medicated is the perfect shampoo for dandruff and itchy scalp. This shampoo is a clinically proven solution for controlling dandruff, including flaking, scaling, and itching. It is even powerful enough to manage severe cases of dandruff. Nizoral's active ingredient is 10 times more effective at eliminating scalp fungus than the leading uncontrollable dandruff shampoo, as demonstrated by lab testing. It is gentle enough to use on color-treated, chemically-processed, or gray hair, and has a clean, fresh scent. You only need to use it twice a week to see results. Ketoconazole 1%, a clinically-proven and powerful dandruff-fighting ingredient, is the only over-the-counter dandruff shampoo in Nizoral.This is our top pick as the strongest dandruff shampoo AND the best shampoo for minoxidil dandruff due to the ingredient Ketoconazole. A top pick for best medicated shampoo for severe dandruff.

Head and Shoulders Medicated

Neutrogena T/Gel Therapeutic Shampoo

Neutrogena T/Gel Therapeutic Shampoo: Get relief from itchy and flaky scalp with Neutrogena T/Gel Therapeutic Shampoo Original Formula which is our fave shampoo for stubborn dandruff. This dermatologist-recommended best shampoo for postpartum dandruff fights not only uncontrollable dandruff but also scalp psoriasis, and seborrheic dermatitis after just one use, leaving hair clean and manageable. With 2% Neutar Solubilized coal tar extract, this alcohol-free shampoo is National Psoriasis Foundation recognized for proven effectiveness. Trust Neutrogena T/Gel for long-lasting relief. TGel Target A top pick for best medicated shampoo for severe dandruff and prescription strength shampoo for dandruff. 

Botanic Hearth Tea Tree Shampoo and Conditioner Set

Botanic Hearth Tea Tree Shampoo and Conditioner Set: Botanic Hearth Tea Tree Shampoo and Conditioner set contains ​100% ​natural tea tree oil that provides a calming effect on the scalp, relieves dryness & itchiness while leaving the hair feeling clean & refreshed​. This ultimate hair care set is enriched with nourishing ingredients like chamomile extract, vitamin B5 and E that work together to deeply moisturize and hydrate the hair​. ​Botanic Hearth shampoo and conditioner set helps fight dandruff and scalp irritation, while also nourishing and hydrating the hair, leaving it feeling healthy and refreshed​. ​​This tea tree shampoo helps to strengthen and nourish hair follicles, promoting healthy hair growth while also improving the overall texture of hair​ plus it's: ​​​

• made or packaged in the USA
• safe & healthy
• sulfate, paraben & cruelty-free

Biolage Scalp Sync Anti-Dandruff Shampoo

Biolage Scalp Sync Anti-Dandruff Shampoo: Inspired by the anti-bacterial and calming properties of the Mint Leaf, Biolage Scalp Sync Anti-Dandruff Shampoo with Pyrithione Zinc helps target dandruff, control the appearance of visible flakes and relieves scalp irritation. 

Selsun Blue Medicated Dandruff Shampoo

Selsun Blue Medicated Dandruff Shampoo: If you've asked which selsun blue is best for dandruff, look no further it's this Selsun Blue Medicated Dandruff Shampoo. This Selsun Blue Medicated Anti-dandruff Shampoo for Men is a maximum-strength formula that targets dandruff to prevent and eliminate itchy scalp and visible flakes. Formulated with menthol, it delivers a refreshing and soothing sensation to the scalp. Use at least twice a week for best results and say goodbye to flakes with Selsun Blue. Another best medicated shampoo for severe dandruff, best medicated shampoo for severe dandruff, a prescription strength shampoo for dandruff and a top clinically proven dandruff shampoo.

Dove Dermacare Scalp Dryness & Itch Relief Anti-Dandruff Shampoo

Dove Dermacare Scalp Dryness & Itch Relief Anti-Dandruff Shampoo: This Dove is the best smelling dandruff shampoo and our fave for dandruff shampoo that doesn't stink! Achieve a flake-free hair appearance with regular usage of Dove Dermacare Scalp Dryness & Itch Relief Shampoo. This anti-dandruff shampoo is formulated with Pyrithione Zinc, which is pH balanced to eliminate visible flakes and soothe scalp irritation caused by dryness or itchiness. Enjoy a healthy scalp and hair with this specialized shampoo. This is a top choice for best drugstore shampoo for dandruff.

Free & Clear Medicated Anti-Dandruff Shampoo

Free & Clear Medicated Anti-Dandruff Shampoo: Looking for an effective solution to control and reduce dandruff and seborrheic dermatitis symptoms? Look no further than Free & Clear Medicated Anti-Dandruff Shampoo. This sulfate-free, pyrithione zinc shampoo is formulated with maximum OTC strength zinc pyrithione 2% and contains ingredients recommended by dermatologists that are gentle and non-irritating to the skin. Plus, it's free of dyes, fragrance, masking fragrance, lanolin, parabens, formaldehyde releasers, and is protein, sulfate, and gluten-free. Definitely a top pick for the best medicated shampoo for severe dandruff.

Neutrogena T/Sal Therapeutic Shampoo

Neutrogena T/Sal Therapeutic Shampoo: If you're struggling with scalp psoriasis, seborrheic dermatitis, or dandruff, Neutrogena T/Sal Therapeutic Shampoo with Salicylic Acid might be the solution you need. This drugstore dandruff shampoo contains a clinically proven active ingredient – 3% salicylic acid – that can help clear up crusty scalp build-up and relieve itching and flaking after just one use. This dermatologist-recommended dandruff shampoo is highly effective for severe scalp conditions and offers maximum relief for dry, itchy, and flaky scalps. A top pick for best medicated shampoo for severe dandruff. 

OUAI Detox Shampoo

OUAI Detox Shampoo: OUAI Detox Shampoo is a clarifying cleanse for dirt, oil, product and hard water buildup that helps with uncontrollable dandruff. Get back to super clean, soft and refreshed locks. Get rid of product and hard water buildup, dirt and oil with this 1-2x a week clarifying treatment. This concentrated shampoo  has apple cider vinegar to get you back on good terms with overworked tresses. OTC Dandruff Shampoo

PHILIP B Anti-Flake Relief Shampoo

PHILIP B Anti-Flake Relief Shampoo: For those experiencing unpleasant symptoms such as itching and flaking, the PHILIP B Anti-Flake Relief Shampoo, Coal Tar-Free 7.4 oz. (220 ml) is a product worth considering. This particular dandruff shampoo is formulated with 13.6% pure active plant concentrates, including Aloe Vera, Tea Tree Oil, Sage, Juniper Berry and Chamomile, to promote a healthier scalp. Additionally, it contains a potent mix of 1.25% Zinc Omadine and 0.7% Coal Tar to provide relief from symptoms attributed to dandruff, seborrheic dermatitis, and/or psoriasis. Free of parabens, and safe to use with hair color and keratin treatments. Made with vegan and cruelty-free ingredients. This is our top pick for the best dandruff shampoo for keratin treated hair. Best OTC Dandruff Shampoo

Royal Oils Sulfate-Free Scalp Care Anti-Dandruff Shampoo by Head & Shoulders

Royal Oils Sulfate-Free Scalp Care Anti-Dandruff Shampoo by Head & Shoulders: Head & Shoulders Royal Oils Sulfate-Free Scalp Care Anti-Dandruff Shampoo for Natural, Curly, and Coily Hair, with Coconut Oil and Apple Cider Vinegar, Paraben Free, 12.8 Fl Oz is infused with Coconut Oil and Apple Cider Vinegar and promotes a Healthier Scalp and Healthier Hair in 3 weeks plus it balances and restores scalp health with regular use. Sulfate-free, Paraben-free, and Dye-free. Free of SLS / SLES Sulfates and Parabens. A top pick for best drugstore shampoo for dandruff.

Jupiter Color Safe Anti Dandruff Shampoo

Jupiter Color Safe Anti Dandruff Shampoo: Jupiter Dry Scalp & Dandruff Shampoo a phthalate free dandruff shampoo, gets to the root of dandruff (flaking, irritation, dry scalp, itchy scalp), thanks to the active ingredient, Zinc Pyrithione. For best results, pair our Nourishing Conditioner with this clean dandruff shampoo. It's free from sulfates, parabens, phthalates, and dyes, and is designed to eliminate flakes, soothe irritation, reduce excess sebum, and clear buildup while refreshing the scalp. This is our top recommendation for dandruff shampoo, particularly for those with dyed hair.

Shea Moisture African Black Soap Bamboo Charcoal Deep Cleansing Shampoo

Shea Moisture African Black Soap Bamboo Charcoal Deep Cleansing Shampoo:  This cleanse & calm Shea Moisture African Black Soap Charcoal shampoo treats your scalp and hair with gentle, yet effective deep cleansing sulfate free shampoo; Lift away pre wash treatments, dirt, excess oil and flaky build up as you calm and soothe the scalp
Dryness prone scalp: Helps soothe itching, while revitalizing hair; Leaves scalp rigorously clean, yet comfortable, creating an ideal environment for healthy hair. Made with Fair Trade Shea Butter and contains : African Black Soap, Bamboo Charcoal, Tea Tree Oil. No sulfates, no parabens, no phthalates, no propylene glycol, no mineral oil, no animal testing and no petroleum products.

ACURE Curiously Clarifying Shampoo

ACURE Curiously Clarifying Shampoo: Treat your hair to a refreshing cleanse with Acure's Dandruff Shampoo. Infused with lemongrass and double-doses of beneficial oils, this shampoo is gentle enough for daily use. Plus, it's 100% vegan and free of harmful ingredients like Parabens, Sulfates, Mineral Oil, Petrolatum, and Formaldehyde. Rest assured that this cruelty-free shampoo is a safe and responsible choice for your hair care routine.

Briogeo Scalp Revival MegaStrength + Dandruff Shampoo

Briogeo Scalp Revival MegaStrength + Dandruff Shampoo: Briogeo dandruff shampoo treatment helps eliminate and prevent the recurrence of scalp itching, irritation, redness, and flaking due to dandruff, psoriasis, and seborrheic dermatitis. Formulated with detoxifying Binchotan charcoal and scalp soothing tea tree oil. Best OTC Dandruff Shampoo

Bumble and Bumble Full Potential Hair Preserving Shampoo

Bumble and Bumble Full Potential Hair Preserving Shampoo: Bumble and Bumble Dandruff shampoo is an invigorating shampoo that exfoliates the scalp and combats against the visible signs of hair loss due to breakage creating an optimal environment to restore damaged hair. 

How to Use Anti-Dandruff Shampoo

To effectively use drugstore dandruff shampoo and to fight uncontrollable dandruff, begin by wetting your hair and gently applying the product to your scalp. It is recommended that you massage the shampoo into your scalp for 1-2 minutes before rinsing it off. Consistent use of the shampoo for several weeks may be necessary to achieve optimal results.

For optimal results, it's crucial to regularly utilize anti-dandruff shampoo. Generally, it takes around 2-4 weeks of consistent use to notice a significant change. Following treatment for dandruff, switch to a non-medicated shampoo to prevent recurrence.

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Common Ingredients in Prescription Strength Shampoo for Dandruff

• Selenium sulfide
• Pyrithione zinc
• Ketoconazole
• Coal tar

There are certain ingredients that have proven effective in treating severe dandruff and itchy scalp, but it's important to note that they may also have some negative side effects, like dryness, irritation, or even hair loss. Clinically proven dandruff shampoo is important for many reasons. If you have any concerns or doubts about using anti-dandruff shampoo, straightaway discuss your options with your doctor or dermatologist.

Paul Mitchell Tea Tree Lavender Mint Moisturizing Shampoo and Conditioner

Tips for Choosing a Drugstore Dandruff Shampoo

• Look for a shampoo that contains one of the active ingredients listed above.
• Choose a shampoo that is gentle on your hair and scalp.
• Read the label carefully and follow the directions.
• If you have any concerns, talk to your doctor or dermatologist.

Tips for Using an Anti-Dandruff Shampoo

• To start, apply the clinically proven dandruff shampoo to wet hair and scalp.
• Massage it in for 1-2 minutes.
• Rinse it thoroughly.
• Use the shampoo as directed on the label.
• Continue using the best medicated shampoo for severe dandruff for at least 2 weeks after your dandruff is gone to prevent it from coming back.

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How does Drugstore Dandruff Shampoo Compare?

• Head and Shoulders vs Selsun Blue – we prefer H&S due to scent
• Head and Shoulders vs nizoral – we prefer H&S due to scent
• Nizoral vs Head and Shoulders – we prefer H&S due to scent
• Nizoral vs T Sal – we prefer Nizoral due to results
• Nizoral vs Selsun Blue – we prefer Selsun Blue due to overall scent and results
• Selsun Blue vs T Gel – we prefer Selsun Blue due to overall scent and results
• Selsun Blue vs Head and Shoulders – we prefer Head & Shoulders over most products
• Selsun Blue vs nizoral – we prefer Selsun Blue due to overall scent and results
• T Gel vs Selsun Blue – we prefer Selsun Blue due to overall scent and results
• T Gel vs Nizoral – we prefer Nizoral due to results

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FAQ's About Severe Dandruff and Itchy Scalp for Drugstore Dandruff Shampoo

• What is the healthiest dandruff shampoo? We use Head & Shoulders as it's a clinically proven dandruff shampoo and it works for severe dandruff and itchy scalp so much that we use it on our dogs too. 
• Does putting conditioner on scalp cause dandruff? Not at all. 
• Can I buy Head and Shoulders with selenium sulfide? Yes you can. In fact, selenium sulphide is the active ingredient in the Head & Shoulders Clinically Proven Solutions range.

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• What is the best anti dandruff shampoo for keratin treated hair? L'Oreal Paris EverPure Sulfate Free Scalp Care Detox 
• Do I need anti dandruff shampoo without sulfate and parabens? Yes. Nizoral Psoriasis shampoo + conditioner formula is free of ingredients that may be irritating including parabens, preservatives, sulfates and alcohol.

Is Head and Shoulders shampoo good for dogs?

Is Head and Shoulders shampoo good for dogs? Yes! We use it on one of our dogs who has severe dandruff and itchy scalp. A lot of groomers swear by H & S saying Zinc Pyrithione ZPT active ingredient water soluble. has the same effect on dogs that it has on our skin. It's also effective against fleas, bacteria and fungal infections, yeast infections.

Dandruff shampoo is also great for our dogs so we always need to have a few bottles on hand. As always, please read reviews and make certain that ALL ingredients in any shampoo and conditioner are safe for you. Double check if you have any allergies. Uncontrollable dandruff may be a medical issue. 

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• What is dandruff shampoo no sulfates? ‌Look for shampoo with NO SULFATES. Why? Sulfate is a group of mineral salts that can have a natural or human-made origin and as a result they can be too effective at washing away oil, which can leave hair or skin feeling parched. And if your skin or scalp is particularly sensitive, sulfates can cause irritations like redness or itching.
• What type of shampoo is best for treating dandruff? Shampoo that is clinically proven dandruff shampoo. 
• What is the best drugstore shampoo for dandruff? Head & Shoulders shampoo hands down is our fave over otc shampoo.
• What is the best medicated shampoo for severe dandruff? Selsun Blue. 

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With severe dandruff and itchy scalp, perhaps increase the frequency of using an anti-dandruff shampoo beyond once a week. It is crucial to select a shampoo that is suitable for your scalp condition and hair type. For sensitive skin try a fragrance-free shampoo and consequently for those with color-treated hair should choose a color-safe shampoo.

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When selecting a drugstore dandruff shampoo, factor in the cost and take your severe dandruff and itchy scalp into account. Shampoos vary in price, ranging from $5 to $20, so it's crucial to find an affordable option for uncontrollable dandruff. If you have concerns about dandruff, certainly consult your doctor or dermatologist to help find an anti-dandruff shampoo. You may also require a prescription-strength shampoo. We hope that you love this Best OTC Dandruff Shampoo post and above all happy washing!